Research about Cholera disease Paper Example | Topics and Well Written Essays - 1500 words

About Cholera disease - Research Paper Example The toxin choleragen cause severe diarrhea by disrupting the function of the epithelium of the small intestine. The clinical features of the disease include severe diarrhea which results in loss of body fluids and salts. The persistent diarrhea results in severe dehydration and weakness. The method of diagnosis involves microscopic analysis of feces. The annual incidence of cholera accounts for about 5.5 million worldwide. The annual mortality worldwide is 120 000. The treatment for cholera involves Oral Rehydration Therapy which restores the osmotic balance of the blood and tissue fluids. The only way to prevent cholera infection is to have an access to uncontaminated food and water. (BARUA et al 209-214). Etiology: Cholera is an infectious disease of the small intestine. It is caused by ingesting contaminated food or water, which contains the pathogen Vibrio cholera which is a comma-shaped, motile, Gram negative bacterium. The bacterium produces an enterotoxin which causes rise wat er stools in the individual affected. It can lead to severe dehydration and eventually death if left untreated. The bacterium acts on the intestinal wall to interfere with the flow of sodium and chloride. This flow of the electrolytes causes a misbalance and hence watery diarrhea ensues. Well water, seafood, raw fruits and vegetables along with grains are the possible carriers of the bacterium. The methods of prevention are further highlighted below in the essay (Taylor et al 500-505 ; MayoClinic). Life Cycle: The organism V. cholera has two life cycles – one in the environment and one inside the human body. V. cholera are present in brackish coastal waters and are found attached to copepods (a type of crustacean), as well as chitin-containing shells of crabs, shrimps, and other shellfish. A rise in the temperature of the water creates a favorable environment for the bacterium. The cholera vibrio can also live inside algae, in a dormant state, for years. Sewage tends to encou rage the growth of algae because it contains nutrients. Thus these ‘algal blooms’ also result in the transmission of the disease (MayoClinic). The pathogen multiplies in the intestine, releasing a powerful toxin (CTX) which disrupts the flow of sodium and chloride ions. The disruption of sodium and chloride ions results in diarrhea which causes rapid loss of water, fluids and salts from the body (rice-water stool) (MayoClinic). There are two serogroups of the bacterium, O-group 1 and O-group 139, and it is their toxigenic strains which are known to cause cholera. V. cholera O1 has two biotypes – Classical and El Tor. Each biotype has two serotypes – Inaba and Ogawa. Individuals infected with El Tor, either do not show any symptoms of the disease, or develop only a mild illness. The classical serotype is now only restricted to Bangladesh and India (WHO; CDC). Contaminated standing water, seafood, raw fruits and vegetables and grains like rice and millet may harbor the bacterium especially in developing countries where there is poor sanitation and the provision of clean drinking water is a formidable challenge. The disease can also be spread by vectors like flies when moving from human feces to food. After being infected with the bacterium 25% of the people develop the disease. The rest remain ‘

Managing Human Resources Master Essay Example | Topics and Well Written Essays - 2750 words

Managing Human Resources Master - Essay Example Traditional human resource methods include but are not limited to placing an add in the newspaper or hiring a head hunter. However, neither effort can specify details of their requirements in a cost-effective way. The purchase of a advertisement leaves the employer unable to afford to pack in so much information in a print add. Traditional recruitment methods also have higher costs per hire. This is especially so in the case of head hunters who require a percentage of the annual salary of the candidate whom is ultimately hired. Human Resource recruitment has been argued to be the process of attracting the best qualified individuals or candidate to apply for a job. In business, recruitment involves three stages, identify and define the requirements including the job description, job specifications, attract potential employees and make sure the most appropriate people are retain for a particular position (Poole 1999). Human resource selection process can take place either through internal or external method. According to Poole (1999) internal recruitment and selection refers to the filling of job vacancies from within the business here, existing employees are selected rather than employing someone from outside (Poole 1999). A business might decide that it already has the right people with the right skills to do the job, particularly if its training and development programme has been effective (Poole 1999). Poole (1999) went further to states how internal vacancies are usually advertised within the business via a variety of sources such as Staff notice boards Intranets, in-house magazines etc. This internal selection method has largely been applauded because of its growth opportunity given to internal employees. For example, Osborne, Hyman & Jack (2006) stipulated that internal selection processes, gives existing employees greater opportunity to advance their careers in the business and may help to retain staff who might otherwise leave and assist in a situation of a short induction training period (Osborne, Hyman & Jack 2006). On the other hand, external recruitment and selection processes refer to the filling of job vacancies from outside the business (contrast with internal recruitment). Most businesses engage in external recruitment fairly frequently, particularly those that are growing strongly, or that operate in industries with high staff turnover (Poole 1999, Osborne, Hyman & Jack 2006). Most often, organizations used several ways to look for staff externally. Some used external agencies, some headhunts, while others use job recruitment and student placement fare (Poole 1999). The main advantages with using an agency are the specialist skills they bring and the speed with which they normally provide candidates. They also